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Other symptoms include thickening of the bone structure and accumulation of bone tissue, which both contribute to impaired joint mobility. Ligaments and cartilage can become ossified. [2] Most patients with skeletal fluorosis show side effects from the high fluoride dose such as ruptures of the stomach lining and nausea. [3]
[2] [3] [4] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 mg for a 50 kg person) than lethal doses. [5] Although it is helpful topically for dental health in low dosage, chronic ingestion of fluoride in large amounts interferes with bone formation.
Fluoride is a mainstay of dental care, whether it's delivered in a treatment at your dentist's office or in your toothpaste. But fluoride has become the focus of several conspiracy theories over ...
As primary teeth are being developed, the ingestion of fluoride causes the teeth to form stronger and more resistant to cavities, although this increases the risk of dental fluorosis. [ 10 ] [ 11 ] [ 12 ] Water and milk fluoridation are two forms of systemic fluoride therapy that are effective at preventing dental cavities.
Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...
Dental fluorosis is caused by a higher than normal amount of fluoride ingestion whilst teeth are forming. Primary dentine fluorosis and enamel fluorosis can only happen during tooth formation, so fluoride exposure occurs in childhood. Enamel fluorosis has a white opaque appearance which is due to the surface of the enamel being hypomineralised ...
Fluoride salts, particularly sodium fluoride (NaF), are used in the treatment and prevention of osteoporosis. [13] Symptoms such as fractured hips in the elderly or brittle and weak bones may be caused by fluorine deficiency in the body. [14] Fluoride stimulates bone formation and increases bone density; [15] however, bone with excess fluoride ...
Also, although fluoride affects the physiology of dental bacteria, [90] its effect on bacterial growth does not seem to be relevant to cavity prevention. [91] Fluoride's effects depend on the total daily intake of fluoride from all sources. [13] About 70–90% of ingested fluoride is absorbed into the blood, where it distributes throughout the ...