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A smart insulin patch, also known as a glucose-responsive insulin patch, is a type of wearable medical device for diabetes treatment. It is a transdermal patch comprising glucose-sensitive microneedle-array loaded with insulin for blood glucose regulation.
Nanomedicine seeks to deliver a valuable set of research tools and clinically useful devices in the near future. [ 4 ] [ 5 ] The National Nanotechnology Initiative expects new commercial applications in the pharmaceutical industry that may include advanced drug delivery systems, new therapies, and in vivo imaging. [ 6 ]
This means of delivery is largely founded on nanomedicine, which plans to employ nanoparticle-mediated drug delivery in order to combat the downfalls of conventional drug delivery. These nanoparticles would be loaded with drugs and targeted to specific parts of the body where there is solely diseased tissue, thereby avoiding interaction with ...
enhancing targeted intracellular delivery to ensure the treatments reach the correct structures inside cells; combining diagnosis and treatment. [2] The development of new drug systems is time-consuming; it takes approximately seven years to complete fundamental research and development before advancing to preclinical animal studies. [3]
Nanocarriers range from sizes of diameter 1–1000 nm, [3] [4] however due to the width of microcapillaries being 200 nm, nanomedicine often refers to devices <200 nm. [4] Because of their small size, nanocarriers can deliver drugs to otherwise inaccessible sites around the body.
The device automatically adjusts a patient's basal insulin delivery. [7] It is made up of a continuous glucose monitor, an insulin pump, and a glucose meter for calibration. It automatically functions to modify the level of insulin delivery based on the detection of blood glucose levels by continuous monitor.
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