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Rhinitis medicamentosa (or RM, also known as rebound congestion) is a condition of rebound nasal congestion suspected to be brought on by extended use of topical decongestants (e.g., oxymetazoline, phenylephrine, xylometazoline, and naphazoline nasal sprays) and certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the ...
Clinical trial number NCT02870205 for "Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301-304)" at ClinicalTrials.gov v t
Side effects. Topical decongestants should not be used for longer than a week as prolonged use may result in rhinitis medicamentosa (rebound nasal congestion). [13] Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12]
Xylometazoline, also spelled xylomethazoline, is a medication used to reduce symptoms of nasal congestion, allergic rhinitis, and sinusitis. [2] It is used directly in the nose as a spray or drops. [3] Side effects include trouble sleeping, irritation of the nose, nausea, nosebleed (3%), period pain (10%) and headache (3%).
It is used as eye drops or as a nasal spray. [2] The eye drops generally result in an improvement within half an hour. [2] Common side effects include headache, sore throat, eye discomfort, or changes in perception of taste. [3] [2] More significant side effects may include sleepiness. [2] It is unclear if use during pregnancy or breastfeeding ...
Ainslie says one of the things that makes nasal spray options so exciting is the ease of delivery — which can be a lifesaver in an emergency like an opioid overdose or an allergic reaction.