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Oropharyngeal cancer, [1] [2] [3] also known as oropharyngeal squamous cell carcinoma and tonsil cancer, [1] is a disease in which abnormal cells with the potential to both grow locally and spread to other parts of the body are found in the oral cavity, in the tissue of the part of the throat that includes the base of the tongue, the tonsils, the soft palate, and the walls of the pharynx.
HPV+OPC presents in one of four ways: as an asymptomatic abnormality in the mouth found by the patient or a health professional such as a dentist; with local symptoms such as pain or infection at the site of the tumor; with difficulties of speech, swallowing, and/or breathing; or as a swelling in the neck (if the cancer has spread to lymph nodes).
[1] [14] [15] Their tonsils – and often the back of the throat – appear red and swollen, and sometimes give off a white discharge. [1] [15] [16] Some also have tender swelling of the cervical lymph nodes. [1] [15] Many viral infections that cause tonsillitis will also cause cough, runny nose, hoarse voice, or blistering in the mouth or ...
Lymphoma, a cancer of the immune system, can also present with swollen tonsils: “It can be on one or both sides, often with lumps or lymph nodes in the neck, armpits, or groin,” says Dr. Zalvan.
The stages of oropharyngeal cancer are as follows: [23] • Stage 0 (carcinoma in situ): This stage indicates a good prognosis as most patients with stage 0 survive for a long period without the requirement of an intensive treatment. Although, the patient must cease smoking as it can increase the risk of developing a new cancer.
Oral mucositis is a common and often debilitating complication of cancer treatment. [3] Oral and gastrointestinal (GI) mucositis affects almost all patients undergoing high-dose chemotherapy and hematopoietic stem cell transplantation (HSCT), 80% of patients with cancers of the head and neck receiving radiotherapy, and a wide range of patients ...