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[3] [4] Cannabidiol (CBD) is another major constituent of some cannabis plants. [5] Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C (480 to 570°F), potentially leading to its partial transformation into THC. [6] At least 113 distinct cannabinoids have been isolated from cannabis. [7]
Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. [16] Medically, it is an anticonvulsant used to treat multiple forms of epilepsy. [4]
On October 31, 2017, the FDA sent warning letters to four CBD marketers, including Stanley Brothers Social Enterprises, LLC (d/b/a CW Hemp), the producer of Charlotte's Web. They were warned "against making medical claims about cannabidiol (CBD). The agency also took issue with the businesses marketing CBD products as dietary supplements". [43]
Cannabis plant. Cannabis flower essential oil, also known as hemp essential oil, is an essential oil obtained by steam distillation from the flowers, panicles (flower cluster), stem, and upper leaves of the hemp plant (Cannabis sativa L.). [1]
As of 2017, the hemp industry estimated that annual sales of hemp products were around $820 million annually; hemp-derived CBD have been the major force driving this growth. [ 140 ] Despite this progress, hemp businesses in the US have had difficulties expanding as they have faced challenges in traditional marketing and sales approaches.
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Synthetic cannabinoids, or neocannabinoids, are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants attach. [1] These novel psychoactive substances should not be confused with synthetic phytocannabinoids (obtained by chemical synthesis ) or synthetic ...
Despite the CBD and THC having the same molecular weight, multiple analytical methods are able to differentiate them. [11] "on the recovery of both THC (86.7−90.0%) and CBD (92.3−95.6%). The slightly lower recovery of THC can be explained by the fact that THC is less polar than CBD and more likely to remain in the nonpolar sunflower oil." [11]