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Surgery is normally reserved for complications of Crohn's disease or when disease that resists treatment with drugs is confined to one location that can be removed. [30] Surgery is often used to manage complications of Crohn's disease, including fistulae , small bowel obstruction , colon cancer , small intestine cancer and fibrostenotic ...
The association between inflammatory conditions of the eye and Crohn's disease is due to many Crohn's disease patients having genetic markers such as HLA-B07, HLA-B27 and HLA-DRB1*0103. [57] Additionally, cytokines IL-6, IL-10, and IL-17 which are produced in the bowel enter the circulatory system and travel to the eyes to trigger inflammation.
Crohn’s disease and ulcerative colitis, the two main types of IBD, share many of the same symptoms. Per the CDC, common symptoms linked to IBD include diarrhea, stomach pain, fatigue, nausea and ...
However, basic science research showed that many cytokines were elevated in both Crohn's disease and ulcerative colitis. [19] Crohn's disease cytokines are of the type 1 (Th1) cytokines, which include TNF-α, interleukin-2, and interferon γ. [20] Ulcerative colitis was less conclusively linked to the production of Th2 cytokines. [21]
Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. [2] Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn's disease, and ulcerative colitis.
Azathioprine, sold under the brand name Imuran, among others, is an immunosuppressive medication. [5] It is used for the treatment of rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and systemic lupus erythematosus, and in kidney transplants to prevent rejection.
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