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Therefore, almost all new epilepsy drugs are initially approved only as adjunctive (add-on) therapies. Patients whose epilepsy is uncontrolled by their medication (i.e., it is refractory to treatment) are selected to see if supplementing the medication with the new drug leads to an improvement in seizure control.
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
Seizures may also occur as a consequence of other health problems; [30] if they occur right around a specific cause, such as a stroke, head injury, toxic ingestion, or metabolic problem, they are known as acute symptomatic seizures and are in the broader classification of seizure-related disorders rather than epilepsy itself.
The major cognitive impairment in mesial temporal lobe epilepsy is a progressive memory impairment. [14]: 71 This involves declarative memory impairment, including episodic memory and semantic memory, and is worse when medications fail to control seizures.
A seizure can be disruptive to the process of normal life. During the seizure, depending on the type, the patient may be totally or partially unconscious, and out of commission to perform normal activities. Following the seizure the patient may be confused and disoriented for a period of time. The patient may also require rest after the seizure ...
Syndromes are characterized into 4 groups based on epilepsy type: [1] a. Generalized onset epilepsy syndromes. These epilepsy syndromes have only generalized-onset seizures and include both the idiopathic generalized epilepsies (specifically childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy and epilepsy with generalized tonic- clonic seizures alone), as well as ...
Here's More Evidence That Common Drugs May Cause Cognition Issues. ... More than 400 participants, with an average age of 73, were given memory and cognitive tests, PET scans and MRI scans.
Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. [9] It has also been used for alcohol dependence and essential tremor. [9] For epilepsy, this includes treatment for generalized or focal seizures. [10] It is taken orally (by mouth). [9]