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In a prior study, 20 of 31 patients became seizure-free with anti-seizure medication, and valproic acid was the most effective drug. Lamotrigine and ethosuximide also showed success. [3] There are recognised "rescue therapies" for seizures, medications given quickly while a seizure occurs. [5] Such treatment may reduce or prevent serial ...
Therefore, almost all new epilepsy drugs are initially approved only as adjunctive (add-on) therapies. Patients whose epilepsy is uncontrolled by their medication (i.e., it is refractory to treatment) are selected to see if supplementing the medication with the new drug leads to an improvement in seizure control.
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
The major cognitive impairment in mesial temporal lobe epilepsy is a progressive memory impairment. [14]: 71 This involves declarative memory impairment, including episodic memory and semantic memory, and is worse when medications fail to control seizures.
Seizures may also occur as a consequence of other health problems; [30] if they occur right around a specific cause, such as a stroke, head injury, toxic ingestion, or metabolic problem, they are known as acute symptomatic seizures and are in the broader classification of seizure-related disorders rather than epilepsy itself.
Lyme encephalopathy: Arising from Lyme disease bacteria, including Borrelia burgdorferi. Toxic encephalopathy: A form of encephalopathy caused by chemicals and prescription drugs, often resulting in permanent brain damage. Toxic-metabolic encephalopathy: A catch-all for brain dysfunction caused by infection, organ failure, or intoxication.
A link between these types of drugs and cognitive impairment isn't a totally new discovery, but for the first time, researchers used brain imaging techniques to determine the physical changes ...
Memory difficulties are among the most common issues for people with epilepsy, [14] and "persistent memory impairment is reported by about 75% of patients with TEA." [13] Other studies suggest the rate exceeds 80%. [2] People who have had TEA attacks frequently report three kinds of persistent problems with memory: accelerated long term forgetting