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Chromium toxicity refers to any poisonous toxic effect in an organism or cell that results from exposure to specific forms of chromium—especially hexavalent chromium. [1] Hexavalent chromium and its compounds are toxic when inhaled or ingested. Trivalent chromium is a trace mineral that is essential to human
Chromium supplementation in general is subject to a certain amount of controversy as it is by no means clear that chromium is an essential element in human biology. [25] Nevertheless, chromium is an ingredient in total parenteral nutrition, along with other trace minerals. [26] It is also in nutritional products for preterm infants. [27]
The river water was contaminated with toxic metals including arsenic, copper, barium, cadmium, chromium, lead, mercury, nickel, and thallium. [2] Cleanup costs may exceed $1.2 billion. [3] A toxic heavy metal is a common but misleading term for a metal-like element noted for its potential toxicity. [4]
California has set a limit for the toxic heavy metal hexavalent chromium in drinking water. Advocates have called for a stricter limit, warning of health risks.
This study looks at chronic oral exposure of hexavalent chromium in rats, and its association with cancer. The other study mentioned is a human health assessment of chromium, titled Toxicological Review of Hexavalent Chromium. The final human health assessment is currently in the stage of draft development. [47] This stage is the first of seven.
Ingestion of, or exposure to, excessive quantities can be toxic. However, insufficient plasma or tissue levels of certain trace metals can cause pathology, as is the case with iron. Trace metals within the human body include iron, lithium, zinc, copper, chromium, nickel, cobalt, vanadium, molybdenum, manganese and others. [1] [2] [3]
Mineral deficiency is a lack of the dietary minerals, the micronutrients that are needed for an organism's proper health. [1] The cause may be a poor diet, impaired uptake of the minerals that are consumed, or a dysfunction in the organism's use of the mineral after it is absorbed.
Chromium, especially hexavalent chromium, is highly toxic to fish because it is easily absorbed across the gills, readily enters blood circulation, crosses cell membranes and bioconcentrates up the food chain. In contrast, the toxicity of trivalent chromium is very low, attributed to poor membrane permeability and little biomagnification. [141]