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High levels of prolactin in the blood (which may occur as a result of certain tumors or as a side effect of certain medications) has been associated with gynecomastia. [26] A high level of prolactin in the blood can inhibit the release of gonadotropin-releasing hormone and therefore cause secondary hypogonadism.
Gynecomastia can cause your nipples to become swollen or tender. You might feel an enlargement in the glandular tissue behind one or both of your nipples. ... Using (or abusing) certain drugs like ...
Mammoplasia can be an effect or side effect of various drugs, including estrogens, [2] [13] antiandrogens such as spironolactone, [14] cyproterone acetate, [15] bicalutamide, [16] [17] and finasteride, [18] [19] growth hormone, [20] [21] and drugs that elevate prolactin levels such as D 2 receptor antagonists like antipsychotics (e.g ...
Gynecomastia induced by spironolactone usually regresses after a few weeks following discontinuation of the medication. [110] However, after a sufficient duration of gynecomastia being present (e.g., one year), hyalinization and fibrosis of the tissue occurs and drug-induced gynecomastia may become irreversible.
Gynecomastia, or male breast enlargement (reported by 0.5 percent of men) Breast tenderness (reported by 0.4 percent of men) ... For example, if a person is aware that a medication can cause ...
Some of its side effects, including breast pain/tenderness and gynecomastia, are far less likely to occur when the drug is combined with a GnRH analogue, [205] while certain other side effects, including hot flashes, depression, fatigue, and sexual dysfunction, [206] occur much more frequently in combination with a GnRH analogue.
The drug may cause adrenal insufficiency so the level of the adrenocortical hormones should be monitored while taking it. [ 13 ] [ 36 ] Oral ketoconazole at a dosage range of 400 to 2,000 mg/day has been found to result in a rate of gynecomastia of 21%.
The rates of gynecomastia in men with selective AR antagonist monotherapy have been found to range from 30 to 85%. [102] In addition, antiandrogens can cause infertility, osteoporosis, hot flashes, sexual dysfunction (including loss of libido and erectile dysfunction), depression, fatigue, anemia, and decreased semen/ejaculate volume in males.