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Examples of viral inclusion bodies in plants [13] include aggregations of virus particles (like those for Cucumber mosaic virus [14]) and aggregations of viral proteins (like the cylindrical inclusions of potyviruses [15]). Depending on the plant and the plant virus family these inclusions can be found in epidermal cells, mesophyll cells, and ...
Type-A inclusion bodies are found only in certain poxviruses like cowpox. [3] The Guarnieri bodies are found in all poxvirus infections and their presence is diagnostic. [ 4 ] The diagnosis of an orthopoxvirus infection can also be made rapidly by electron microscopic examination of pustular fluid or scabs.
A viroplasm, sometimes called "virus factory" or "virus inclusion", [1] is an inclusion body in a cell where viral replication and assembly occurs. They may be thought of as viral factories in the cell. There are many viroplasms in one infected cell, where they appear dense to electron microscopy. Very little is understood about the mechanism ...
Cytomegalic inclusion body disease (CIBD) also known as cytomegalic inclusion disease (CID) is a series of signs and symptoms caused by cytomegalovirus infection, toxoplasmosis or other rare infections such as herpes or rubella viruses. It can produce massive calcification of the central nervous system, and often the kidneys. [1]
The inclusion bodies can first be identified by light microscopy in patient blood smears or stained sections of infected tissues. However, to fully characterize their composition, electron microscopy must be performed. Inclusion bodies may either be accumulation of virus replication byproducts or altered host cell organelles or structures. [3]
Negri bodies are eosinophilic, sharply outlined, pathognomonic inclusion bodies (2–10 μm in diameter) found in the cytoplasm of certain nerve cells containing the virus of rabies, especially in pyramidal cells [1] within Ammon's horn of the hippocampus.
B-type inclusions, formerly known as Guarnieri bodies / ɡ w ɑːr n ˈ j ɛər i / are cellular features found upon microscopic inspection of epithelial cells of individuals suspected of having poxvirus [1] (e.g. smallpox [2] or vaccinia). In cells stained with eosin, they appear as pink blobs in the cytoplasm of affected epithelial cells.
Histological slide of the human herpes virus-6 showing infected cells, with inclusion bodies in both the nucleus and the cytoplasm. Inclusion bodies were first described in the late 19th and 20th centuries. One of the earliest figures associated with the discovery of inclusion bodies is Fritz Heinrich Jakob Lewy.