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OPKO Health (OPK) gets FDA nod for its 4Kscore Test that will further validate its value of being an important tool in the diagnosis of prostate cancer.
The 4Kscore combines total, free and intact PSA together with human kallikrein 2. [46] It is used to try to determine the risk of a Gleason score greater than 6. [46] The Prostate Health Index (PHI) is a PSA-based blood test for early prostate cancer screening. It may be used to determine when a biopsy is needed.
Earlier this year, OPKO executed a sublicensing deal with IHT to commercialize OPKO's novel panel of kallikrein biomarkers and associated algorithm (4Kscore™) for the early detection of prostate ...
If the correlation between separate administrations of the test is high (e.g. 0.7 or higher as in this Cronbach's alpha-internal consistency-table [6]), then it has good test–retest reliability. The repeatability coefficient is a precision measure which represents the value below which the absolute difference between two repeated test results ...
In statistics, intra-rater reliability is the degree of agreement among repeated administrations of a diagnostic test performed by a single rater. [ 1 ] [ 2 ] Intra-rater reliability and inter-rater reliability are aspects of test validity .
A five-level scale for rating quality. Absolute Category Rating (ACR) is a test method used in quality tests. [1] [2] The levels of the scale are, sorted by quality in decreasing order: Excellent; Good; Fair; Poor; Bad; In this method, a single test condition (generally an image or a video sequence) is presented to the viewers once only.
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A range of test have been developed including smartphone based platforms, and tests targeting blood, saliva, faecal matter, urine, and tears have been proposed. [16] Saliva in particular may offer sufficiently high detection rates in tandem with a non-invasive and user friendly procedure, although reliability requires improvement. [17]