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Aquagenic urticaria, also known as water allergy and water urticaria, is a form of physical urticaria in which hives develop on the skin after contact with water, regardless of its temperature. [1] The condition typically results from contact with water of any type, temperature or additive.
The exact mechanism of the condition is unknown. Some studies have suggested the itching occurs in response to increased fibrinolytic activity in the skin, [5] [6] inappropriate activation of the sympathetic nervous system, [7] increased activity of acetylcholinesterase, [8] [9] or an increase in mast cell degranulation that releases histamine and other chemicals into the body.
Constant scratching causes the skin to thicken. The thickened skin itches, causing more scratching, causing more thickening. Affected area may spread rapidly through the rest of the body. Many hypothesize LSC has a psychosomatic origin. [3] Those predisposed to itch as a response to emotional tensions may be more susceptible to the itch-scratch ...
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Dermatographic urticaria is sometimes called "skin writing", as it is possible to mark deliberate patterns onto the skin. The condition manifests as an allergic-like reaction, causing a warm red wheal to appear on the skin. As it is often the result of scratches, involving contact with other materials, it can be confused with an allergic ...
Chronic and repetitive scratching, picking, or rubbing of the nodules may result in permanent changes to the skin, including nodular lichenification, hyperkeratosis, hyperpigmentation, and skin thickening. Unhealed, excoriated lesions are often scaly, crusted or scabbed.
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