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Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). [1][2] Medicinal chemistry is a highly interdisciplinary science combining ...
The structure–activity relationship (SAR) is the relationship between the chemical structure of a molecule and its biological activity. This idea was first presented by Alexander Crum Brown and Thomas Richard Fraser at least as early as 1868. [1][2] The analysis of SAR enables the determination of the chemical group responsible for evoking a ...
Interactive animation of the structure of ATP. Adenosine triphosphate (ATP) is a nucleoside triphosphate [ 2 ] that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis.
Antimicrobial. An antimicrobial is an agent that kills microorganisms (microbicide) or stops their growth (bacteriostatic agent). [1] Antimicrobial medicines can be grouped according to the microorganisms they act primarily against. For example, antibiotics are used against bacteria, and antifungals are used against fungi.
Biology is the scientific study of life. [1] [2] [3] It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. [1] [2] [3] For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be
A protein is a polyamide. Secondary structure: regularly repeating local structures stabilized by hydrogen bonds. The most common examples are the α-helix, β-sheet and turns. Because secondary structures are local, many regions of different secondary structure can be present in the same protein molecule.
The history of biology traces the study of the living world from ancient to modern times. Although the concept of biology as a single coherent field arose in the 19th century, the biological sciences emerged from traditions of medicine and natural history reaching back to Ayurveda, ancient Egyptian medicine and the works of Aristotle, Theophrastus and Galen in the ancient Greco-Roman world.
Phytochemicals (from Greek phyto, meaning "plant") are chemicals produced by plants through primary or secondary metabolism. [2][3] They generally have biological activity in the plant host and play a role in plant growth or defense against competitors, pathogens, or predators. [2] Phytochemicals are generally regarded as research compounds ...