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  2. Clonidine - Wikipedia

    en.wikipedia.org/wiki/Clonidine

    Clonidine. Clonidine, sold under the brand name Catapres among others, is an α 2A -adrenergic agonist [12] medication used to treat high blood pressure, ADHD, drug withdrawal (alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions. [13]

  3. Clonazepam - Wikipedia

    en.wikipedia.org/wiki/Clonazepam

    Clonazepam, sold under the brand name Klonopin among others, is a benzodiazepine medication used to prevent and treat anxiety disorders, seizures, bipolar mania, agitation associated with psychosis, obsessive–compulsive disorder (OCD), and akathisia. [11]

  4. Lorazepam - Wikipedia

    en.wikipedia.org/wiki/Lorazepam

    a box of Lorazepam Orion (Lorazepam) tablets. Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. [14] It is used to treat anxiety (including anxiety disorders), trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. [14]

  5. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Lorazepam has particularly marked amnesic properties that may make it more effective when amnesia is the desired effect. [ 24 ] : 693 Benzodiazepines are well known for their strong muscle-relaxing properties and can be useful in the treatment of muscle spasms, [ 24 ] : 577–578 although tolerance often develops to their muscle relaxant ...

  6. Muscle relaxant - Wikipedia

    en.wikipedia.org/wiki/Muscle_relaxant

    Clonidine and other imidazoline compounds have also been shown to reduce muscle spasms by their central nervous system activity. Tizanidine is perhaps the most thoroughly studied clonidine analog, and is an agonist at α 2-adrenergic receptors, but reduces spasticity at doses that result in significantly less hypotension than clonidine. [26]

  7. Imidazoline receptor - Wikipedia

    en.wikipedia.org/wiki/Imidazoline_receptor

    Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act. [1] [2] [3] There are three main classes of imidazoline receptor: I 1 is involved in inhibition of the sympathetic nervous system to lower blood pressure, [4] I 2 has as yet uncertain functions but is implicated in several psychiatric conditions, [5] [6] and I 3 regulates insulin secretion.

  8. Nicotinic antagonist - Wikipedia

    en.wikipedia.org/wiki/Nicotinic_antagonist

    A nicotinic antagonist is a type of anticholinergic drug that inhibits the action of acetylcholine (ACh) at nicotinic acetylcholine receptors.These compounds are mainly used for peripheral muscle paralysis in surgery, the classical agent of this type being tubocurarine, [1] but some centrally acting compounds such as bupropion, mecamylamine, and 18-methoxycoronaridine block nicotinic ...

  9. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    A study of 50 patients who attended a benzodiazepine withdrawal clinic found that, after several years of chronic benzodiazepine use, a large portion of patients developed health problems including agoraphobia, irritable bowel syndrome, paraesthesiae, increasing anxiety, and panic attacks, which were not preexisting. The mental health and ...