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The U.S. EPA decided that permethrin was "likely to be carcinogenic to humans" if it was eaten. This decision was based on the structure of permethrin, what happens to it in the body, laboratory tests that caused tumors in mice and evidence of tumors in rats.
Research suggests that permethrin can be found in the blood and urine of workers who wear treated clothing, which means it can be absorbed from clothes into the body.
Permethrin is moderately toxic if ingested, causing abdominal pain, sore throat, nausea and vomiting. If inhaled, permethrin may cause headache, respiratory irritation, difficulty breathing, dizziness, nausea and vomiting.
Permethrin is acutely toxic at high doses in animals and humans (LD 50 for animals is greater than 1 g/kg); the toxicity varies with the cis/trans ratio—the cis isomer being more toxic than the trans isomer. Acute signs of toxicity to the central nervous system include incoordination, ataxia, hyperactivity, convulsions, and finally ...
Scabies rarely infests the scalp of adults, although the hairline, neck, side of the head, and forehead may be infested in older people and in infants. Infants should be treated on the scalp, side of the head, and forehead. Leave the permethrin cream on the skin for 8 to 14 hours. Wash off by taking a shower or bath.
In humans, permethrin's postulated lethal oral dose is 1 to 2 g/kg of human body weight. Although reports of toxicity exist when using permethrin as an insecticide, there are only a few adverse events associated with its topical use.
Depending on the formulation, permethrin is a non-toxic to moderately toxic pesticide. Short-term side effects in sensitive individuals include eye, skin, nose, and throat irritation, and may include breathing problems.
Exposure to Permethrin can cause headache, dizziness, fatigue, excessive salivation, muscle weakness, nausea and vomiting. Permethrin may affect the liver. Permethrin does not burn or burns with difficulty.
Video with important information about the safe use of Permethrin. Learn how to safely use Permenthrin on your clothes to repel insects. CDC’s digital and social media tools, metrics, and mobile & web apps.
P ermethrin is neurotoxic at high doses. It produces a variety of clinical neurotoxic effects in animals. Some of those effects are tremors, salivation, paresthesia, splayed gait, depressed reflexes, and tiptoe gait; reversible axonal injury occurs at high doses (Brammer, 1989; Robinson, 1989a,b).