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Although the chemical formula for THC (C 21 H 30 O 2) describes multiple isomers, [10] the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ 9-tetrahydrocannabinol. It is a colorless oil.
Tetrahydrocannabihexol (Δ 9-THCH, Δ 9-Parahexyl, n-Hexyl-Δ 9-THC) is a phytocannabinoid, the hexyl homologue of tetrahydrocannabinol (THC) which was first isolated from Cannabis plant material in 2020 along with the corresponding hexyl homologue of cannabidiol, [1] [2] though it had been known for several decades prior to this as an isomer of the synthetic cannabinoid parahexyl. [3]
Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
Δ 9-THCB, showed an affinity for the human CB 1 (Ki = 15 nM) and CB 2 receptors (Ki = 51 nM) comparable to that of Δ 9-THC. [1] The formalin test in vivo was performed on Δ 9-THCB in order to reveal possible analgesic and anti-inflammatory properties. [1] The tetrad test in mice showed a partial agonistic activity of Δ 9-THCB toward the CB ...
THC hemisuccinate (Δ 9-THC-O-hemisuccinate, Dronabinol hemisuccinate) is a synthetic derivative of tetrahydrocannabinol, developed in the 1990s. It is a water-soluble prodrug ester which is converted into THC inside the body, and was developed to overcome the poor bioavailability of THC when taken by non-inhaled routes of administration .
Δ 9-Tetrahydrocannabiorcol (Δ 9-THCC, (C1)-Δ 9-THC) is a phytocannabinoid found in Cannabis pollen. [1] It is a homologue of THC and THCV with the alkyl side chain replaced by a smaller methyl group.
The Δ 9 isomer of THCP occurs naturally in cannabis, but in small amounts. A 2021 study reported the content of Δ 9-THCP ranging from 0.0023% to 0.0136% (w/w) (approximately 0.02–0.13 mg/g) without correlation to THC percentage in Δ 9-THC-dominant strains of cannabis; that study failed to detect THCP in CBD-dominant strains. [2] [10]