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Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. [5] This includes bone and joint infections , intra-abdominal infections, certain types of infectious diarrhea , respiratory tract infections , skin infections, typhoid fever , and urinary tract infections , among others. [ 5 ]
Antibiotics include ciprofloxacin and metronidazole, given for 14 days. If symptoms recur after improvement with antibiotics, a second course of antibiotics may be given. If an initial course of antibiotics is ineffective, then mesalamine may be tried. If mesalamine is ineffective, then a course of prednisone may be helpful.
Complicated diverticulitis is treated with antibiotics and may require surgical interventions such as abscess drainage or fistula repair. [8] Pain is managed with antispasmodics or acetaminophen, rather than NSAIDs (ibuprofen, aspirin, etc.). [16] Antibiotics should be used selectively in most cases of uncomplicated diverticulitis.
Diverticulitis typically presents with lower quadrant abdominal pain of a sudden onset. [1] Patients commonly have elevated C-reactive protein and a high white blood cell count. [ 10 ] In Asia it is usually on the right (ascending colon), while in North America and Europe, the abdominal pain is usually on the left lower side (sigmoid colon).
Diverticulitis is defined as diverticular disease with signs and symptoms of diverticular inflammation. Clinical features of acute diverticulitis include constant abdominal pain, localized abdominal tenderness in the left lower quadrant of the abdomen, nausea, vomiting, constipation or diarrhea, fever and leukocytosis .
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Fluoroquinolones are often used for genitourinary tract infections [5] and are widely used in the treatment of hospital-acquired infections associated with urinary catheters. In community-acquired infections , they are recommended only when risk factors for multidrug resistance are present or after other antibiotic regimens have failed.
When diverticula (singular: diverticulum) become sites of inflammation the condition is termed "diverticulitis" and occurs when the diveritcula become infected. This classically causes lower abdominal pain, changes in bowel habits (diarrhea or constipation) and signs of inflammation (fever/chills, nausea/vomiting).