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Clinically, neonates with omphalitis present within the first two weeks of life with signs and symptoms of a skin infection around the umbilical stump (redness, warmth, swelling, pain), pus from the umbilical stump, fever, fast heart rate (tachycardia), low blood pressure (hypotension), somnolence, poor feeding, and yellow skin ().
Umbilical granuloma is the most common umbilical abnormality in newborn children or neonates, causing inflammation and drainage. [1] [2] [3] It may appear in the first few weeks of newborn infants during the healing process of the umbilical cord due to an umbilical mass. [4] It is the overgrowth of the umbilical tissue. [5]
The umbilical cord lining is a good source of mesenchymal and epithelial stem cells. Umbilical cord mesenchymal stem cells (UC-MSC) have been used clinically to treat osteoarthritis, autoimmune diseases, and multiple other conditions. Their advantages include a better harvesting, and multiplication, and immunosuppressive properties that define ...
772.3 Umbilical hemorrhage after birth; 772.4 Gastrointestinal hemorrhage of fetus or newborn; 772.5 Adrenal hemorrhage of fetus or newborn; 772.6 Cutaneous hemorrhage of fetus or newborn; 772.8 Other specified hemorrhage of fetus or newborn; 772.9 Unspecified hemorrhage of newborn; 773 Hemolytic disease of fetus or newborn, due to isoimmunization
Professor Lisa Askie, senior author of the study, said: “Our findings highlight that particular care should be taken to keep premature babies warm when deferring umbilical cord clamping.
It usually occurs through infection of the unhealed umbilical stump, particularly when the stump is cut with a non-sterile instrument. Neonatal tetanus mostly occurs in developing countries, particularly those with the least developed health infrastructure. It is rare in developed countries. [1]
Bacteria found in the maternal gastrointestinal or gastrourinary tracts can commonly lead to neonatal infection. Bacterial infections may present as fetal distress at birth (including signs of tachycardia, temperature instability or difficulty breathing), neonatal sepsis, or neonatal meningitis.
Besides placenta previa and placental abruption, uterine rupture can occur, which is a very serious condition leading to internal or external bleeding. Bleeding from the fetus is rare, but may occur with two conditions called vasa previa and velamentous umbilical cord insertion where the fetal blood vessels lie near the placental insertion site unprotected by Wharton's jelly of the cord. [11]