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HIV Drug Resistance Database, also known as Stanford HIV RT and Protease Sequence Database, is a database at Stanford University that tracks 93 common mutations of HIV.It has been recompiled in 2008 listing 93 common mutations, after its initial mutation compilation in 2007 of 80 mutations.
The risk of transmission from mother to child is proportional to the plasma viral load of the mother. Untreated mothers with a viral load >100,000 copies/ml have a transmission risk of over 50%. [65] The risk when viral loads are < 1000 copies/ml are less than 1%. [66]
Nucleic-acid-based tests amplify and detect one or more of several target sequences located in specific HIV genes, such as HIV-I GAG, HIV-II GAG, HIV-env, or the HIV-pol. [32] [33] Since these tests are relatively expensive, the blood is screened by first pooling some 8–24 samples and testing these together; if the pool tests positive, each ...
Mature HIV protease exists as a 22 kDa homodimer, with each subunit made up of 99 amino acids. [1] A single active site lies between the identical subunits and has the characteristic Asp-Thr-Gly (Asp25, Thr26 and Gly27) catalytic triad sequence common to aspartic proteases. [8]
The woman accused of stabbing a postal worker to death over a spot in line at a Harlem deli has a long history of knife violence — and once threatened “to cut” one of her previous victims.
Overplanning the holidays can cause stress and wreck what's supposed to be a joyous time. (Tanja Ivanova/Moment RF/Getty Images)
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