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The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin.
The skin is one of the largest organs of the body. In humans, it accounts for about 12 to 15 percent of total body weight and covers 1.5 to 2 m 2 of surface area. [1] 3D still showing human integumentary system. The skin (integument) is a composite organ, made up of at least two major layers of tissue: the epidermis and the dermis. [2]
The word skin originally only referred to dressed and tanned animal hide and the usual word for human skin was hide. Skin is a borrowing from Old Norse skinn "animal hide, fur", ultimately from the Proto-Indo-European root *sek-, meaning "to cut" (probably a reference to the fact that in those times animal hide was commonly cut off to be used as garment).
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
The subcutaneous tissue (from Latin subcutaneous 'beneath the skin'), also called the hypodermis, hypoderm (from Greek 'beneath the skin'), subcutis, or superficial fascia, [2] is the lowermost layer of the integumentary system in vertebrates. [3] The types of cells found in the layer are fibroblasts, adipose cells, and macrophages.
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermis layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
The skin of the body is also host to billions of commensal organisms as well as immune cells. [5] Not all parts of the body are made from cells. Cells sit in an extracellular matrix that consists of proteins such as collagen , surrounded by extracellular fluids.
The word ectoderm comes from the Greek ektos meaning "outside", and derma meaning "skin". [2] Generally speaking, the ectoderm differentiates to form epithelial and neural tissues (spinal cord, nerves and brain). This includes the skin, linings of the mouth, anus, nostrils, sweat glands, hair and nails, [3] and tooth enamel. Other types of ...