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  2. Leukoencephalopathy with vanishing white matter - Wikipedia

    en.wikipedia.org/wiki/Leukoencephalopathy_with...

    The MRI of patients with VWM shows a well defined leukodystrophy. These MRIs display reversal of signal intensity of the white matter in the brain. Recovery sequences and holes in the white matter are also visible. [4] Over time, the MRI is excellent at showing rarefaction and cystic degeneration of the white matter as it is replaced by fluid.

  3. Leukodystrophy - Wikipedia

    en.wikipedia.org/wiki/Leukodystrophy

    While the disease is fatal, the age of onset is a key factor, as infants have a typical life expectancy of 2–8 years, while adults typically live more than a decade after onset. Treatment options are limited, although hematopoietic stem cell transplantations using bone marrow or cord blood seem to help in certain leukodystrophy types, while ...

  4. Leukoencephalopathy - Wikipedia

    en.wikipedia.org/wiki/Leukoencephalopathy

    Leukoencephalopathy with vanishing white matter; Leukoencephalopathy with neuroaxonal spheroids; Reversible posterior leukoencephalopathy syndrome; Megalencephalic leukoencephalopathy with subcortical cysts. It can also refer to gene MLC1 or Megalencephalic leukoencephalopathy with subcortical cysts 1, a human gene related to the former disease.

  5. Progressive multifocal leukoencephalopathy - Wikipedia

    en.wikipedia.org/wiki/Progressive_multifocal_leu...

    PML is diagnosed in a patient with a progressive course of the disease, finding JC virus DNA in spinal fluid together with consistent white-matter lesions on brain magnetic resonance imaging (MRI); alternatively, a brain biopsy is diagnostic [1] when the typical histopathology of demyelination, bizarre astrocytes, and enlarged oligodendroglial ...

  6. Hereditary diffuse leukoencephalopathy with spheroids

    en.wikipedia.org/wiki/Hereditary_diffuse_leuko...

    HDLS falls under the category of brain white matter diseases called leukoencephalopathies that are characterized by some degree of white matter dysfunction. HDLS has white matter lesions with abnormalities in myelin sheath around axons, where the causative influences are being continually explored based upon recent genetic findings. Studies by ...

  7. Acute myeloid leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_myeloid_leukemia

    A syndrome similar to disseminated intravascular coagulation can develop during the initial few days of treatment or at the time the leukemia is diagnosed, and treatment can be complicated by a differentiation syndrome characterised by fever, fluid overload and low oxygen levels. [63] Acute promyelocytic leukemia is considered curable. [64]

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