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lung cancer and mesothelioma: NP cisplatin, vinorelbine: non-small cell lung carcinoma PACE platinum agent, doxorubicin (Adriamycin), cyclophosphamide, etoposide: PCV Procarbazine, CCNU , vincristine: brain tumors: PEB cisplatin, etoposide, bleomycin: non-seminomatous germ cell tumors PEI cisplatin, etoposide, ifosfamide: small-cell lung carcinoma
In males, researchers suggest that the overall reduction in cancer death rates is due in large part to a reduction in tobacco use over the last half century, estimating that the reduction in lung cancer caused by tobacco smoking accounts for about 40% of the overall reduction in cancer death rates in men and is responsible for preventing at least 146,000 lung cancer deaths in men during the ...
Of note, temozolomide yielded a response rate of 38% for brain metastases due to SCLC. [63] In a clinical trial of 50 patients, combination of olaparib and temozolomide in relapsed small-cell lung cancer yielded an overall response rate of 41.7%, median progression-free survival 4.2 months, and overall survival was 8.5 months. [64]
A brain metastasis is a cancer that has metastasized (spread) to the brain from another location in the body and is therefore considered a secondary brain tumor. [ 1 ] [ 2 ] The metastasis typically shares a cancer cell type with the original site of the cancer. [ 3 ]
In 2016, the FDA approved atezolizumab for the treatment of people with metastatic non-small cell lung cancer (NSCLC) whose disease progressed during or following platinum-containing chemotherapy and pembrolizumab for the treatment of people with metastatic non-small cell lung cancer (NSCLC) whose tumors express programmed death-ligand 1 as ...
Unlike extensive-stage small cell lung cancer, limited-stage small cell lung cancer is potentially curable. [4] In limited small cell lung cancer, the median overall survival time is approximately 12–16 months, with five year survival rate of approximately 26% and long-term survival rate of approximately 4–5%. [19]
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