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Methanol toxicity (also methanol poisoning) is poisoning from methanol, characteristically via ingestion. [1] Symptoms may include an altered/decreased level of consciousness, poor or no coordination, vomiting, abdominal pain, and a specific smell on the breath. [1] [2] Decreased vision may start as early as twelve hours after exposure. [2]
If as little as 10 ml of pure methanol is ingested, for example, it can break down into formic acid, which can cause permanent blindness by destruction of the optic nerve, and 30 ml is potentially fatal, [2] although the median lethal dose is typically 100 ml (3.4 fl oz) (i.e. 1–2 ml/kg body weight) of pure methanol. [3]
The list was consolidated and republished in Directive 2001/59/EC, [1] where translations into other EU languages may be found. These risk phrases are used internationally, not just in Europe, and there is an ongoing effort towards complete international harmonization using the Globally Harmonized System of Classification and Labelling of ...
Precautionary statements are one of the key elements for the labelling of containers under the GHS, along with: [4] an identification of the product; one or more hazard pictograms (where necessary) a signal word – either Danger or Warning – where necessary; hazard statements, indicating the nature and degree of the risks posed by the product
Methanol and its vapours are flammable. Moderately toxic for small animals – Highly toxic to large animals and humans (in high concentrations) – May be fatal/lethal or cause blindness and damage to the liver, kidneys, and heart if swallowed – Toxicity effects from repeated over exposure have an accumulative effect on the central nervous system, especially the optic nerve – Symptoms may ...
Risk and Safety Statements, also known as R/S statements, R/S numbers, R/S phrases, and R/S sentences, is a system of hazard codes and phrases for labeling dangerous chemicals and compounds. The R/S statement of a compound consists of a risk part (R) and a safety part (S), each followed by a combination of numbers. Each number corresponds to a ...
A report from the U.S. surgeon general suggested that labels on alcoholic drinks should warn about cancer risk. Doctors expressed their agreement. For people wondering about the long-term damage ...
Statements which correspond to related hazards are grouped together by code number, so the numbering is not consecutive. The code is used for reference purposes, for example to help with translations, but it is the actual phrase which should appear on labels and safety data sheets. [4]