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Ischemic stroke represents the fifth most common cause of death in the western world and the number one cause of long-term disability. Until recent times, systemic intravenous fibrinolysis was the only evidence-based therapy for patients with acute onset of stroke due to large vessel occlusion.
An ischemic stroke's main cause is atherosclerosis. [2] Stroke is commonly caused by atherosclerotic large vessel disease and results from local branch occlusion by plaque, artery-to-artery embolism, or in situ thrombosis, with the latter being the most common cause of anterior cerebral artery infarction. [4]
The TOAST (Trial of Org 10172 in Acute Stroke Treatment) classification is based on clinical symptoms as well as results of further investigations; on this basis, a stroke is classified as being due to (1) thrombosis or embolism due to atherosclerosis of a large artery, (2) embolism of cardiac origin, (3) occlusion of a small blood vessel, (4 ...
The National Institutes of Health Stroke Scale (NIHSS) uses pupillary response as a systematic assessment tool to provide a quantitative measure of stroke-related neurologic deficit and to evaluate acuity of stroke patients, determine appropriate treatment, and predict patient outcome. [26]
The degree of aneurysm occlusion is graded on a five-point scale from 0 (no change in the endoaneurysmal flow) to 4 (complete obliteration of the aneurysm). The patency status of the parent artery is evaluated on a three-point scale, from no change in the parent artery diameter to parent artery occlusion. This grading system is used in clinical ...
The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS), is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke and aid planning post-acute care disposition, though was intended to assess differences in interventions in clinical trials. The NIHSS was designed for the National ...
An embolism involves the occlusion of blood vessels by an embolus. [1] Arterial occlusion by an embolus is termed 'arterial embolism'. An embolus is an agent that blocks blood flow by physically obstructing blood vessels. [1] This includes gas bubbles, [18] fatty deposits, amniotic fluid, [19] blood clots, and foreign material. Arterial emboli ...
Total anterior circulation stroke syndrome (TACS) refers to the symptoms of a patient who clinically appears to have had a total anterior circulation infarct, but who has not yet had any diagnostic imaging (e.g. CT Scan) to confirm the diagnosis. It is diagnosed when it causes all 3 of the following symptoms: Higher dysfunction Dysphasia