Ads
related to: pharmacokinetics software free downloadrxnt.com has been visited by 10K+ users in the past month
Search results
Results From The WOW.Com Content Network
The first pharmacokinetic model described in the scientific literature [2] was in fact a PBPK model. It led, however, to computations intractable at that time. The focus shifted then to simpler models, [3] for which analytical solutions could be obtained (such solutions were sums of exponential terms, which led to further simplifications.)
NONMEM estimates its models according to principles of maximum likelihood estimation. nonlinear mixed-effects model generally do not have close-formed solutions, and therefore specific estimation methods are applied, such as linearization methods as first-order (FO), first-order conditional (FOCE) or the laplacian (LAPL), approximation methods such as iterative-two stage (ITS), importance ...
Pharmacokinetics simulation gives an insight to drug efficacy and safety before exposure of individuals to the new drug that might help to improve the design of a clinical trial. Pharmacokinetics simulations help in addition in therapy planning, to stay within the therapeutic range under various physiological and pathophysiological conditions ...
Lectures on pathophysiology and clinical aspects of diabetes were followed by simulated cases using the AIDA on-line diabetes software simulator. Two cases demonstrated glycemic effects and pharmacokinetics of insulin administration, diet, and exercise in insulin-dependent type 1 diabetes mellitus and non-insulin-dependent type 2 diabetes ...
Software Description Platform License Developer .NET Bio Language-neutral toolkit built using the Microsoft 4.0 .NET Framework to help developers, researchers, and scientists .NET Framework: Apache: Collaborative project AMPHORA: Metagenomics analysis software Linux: GPL: Jonathan Eisen: Anduril: Component-based workflow framework for data analysis
Explore the concept of PK/PD models, which integrate pharmacokinetics and pharmacodynamics to optimize drug dosing and efficacy.
Pharmacokinetics is based on mathematical modeling that places great emphasis on the relationship between drug plasma concentration and the time elapsed since the drug's administration. Pharmacokinetics is the study of how an organism affects the drug, whereas pharmacodynamics (PD) is the study of
VisualSim Architect – an electronic system-level software for modeling and simulation of electronic systems, embedded software and semiconductors. VSim - a multiphysics simulation software tool designed to run computationally intensive electromagnetic, electrostatic, and plasma simulations. zSpace – creates physical science applications