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Both typical and atypical antipsychotics can cause tardive dyskinesia. [50] According to one study, rates are lower with the atypicals at 3.9% as opposed to the typicals at 5.5%. [ 50 ] Although quetiapine and clozapine are atypical antipsychotics, switching to these atypicals is an option to minimize symptoms of tardive dyskinesia caused by ...
In 1986, it was presumed that permanent brain damage may result from chronic use of benzodiazepines similar to alcohol-related brain damage. [ 70 ] In 1987, 17 inpatient people who used high doses of benzodiazepines non-medically have anecdotally shown enlarged cerebrospinal fluid spaces with associated cerebral atrophy .
Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
Seroquel and Seroquel XR – atypical antipsychotic used to treat schizophrenia and bipolar disorder. Used off-label to treat insomnia; Sonata – a non-benzodiazepine hypnotic; Spravato – a rapid-acting antidepressant of the NMDA receptor antagonist class; enantiomer of ketamine
The causes of persisting symptoms are a combination of pharmacological factors such as persisting drug induced receptor changes, psychological factors both caused by the drug and separate from the drug and possibly in some cases, particularly high dose users, structural brain damage or structural neuronal damage.
Drug-induced glomerular disease is not common but there are a few drugs that have been implicated. Glomerular lesions occur primarily through immune-mediated pathways rather than through direct drug toxicity. Heroin and Pamidronate are known to cause focal segmental glomerulosclerosis; Gold salts therapy can cause membranous nephropathy [4 ...