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Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker interstitial cell of Cajal, or similar cells. [2] They are defined as tumors whose behavior is driven by mutations in the KIT gene (85%), [2] PDGFRA gene (10%), [2] or BRAF kinase (rare).
The prognosis for these types of tumors depends heavily on the size of the tumor and the rate of mitosis, however approximately 60 percent of GISTs are diagnosed as benign. [4] Surgery to remove the tumor is the primary treatment method, although imatinib, everolimus, and rapamycin may soon be approved as alternative treatment and management ...
Avapritinib, sold under the brand name Ayvakit among others, is a medication used for the treatment of advanced systemic mastocytosis and indolent systemic mastocytosis. It is also used for the treatment of tumors due to one specific rare mutation: it is specifically intended for adults with unresectable or metastatic gastrointestinal stromal tumor (GIST) that harbor a platelet-derived growth ...
For scientific plotting applications, Gist is a scientific graphics library written in C by David H. Munro of Lawrence Livermore National Laboratory. [ 1 ] [ 2 ] [ 3 ] It supports three graphics output devices: X Window , PostScript , and Computer Graphics Metafiles (CGM).
Ism (name), the Arabic word for a personal name-ism, a suffix appended to many philosophical concepts; Industry Structure Model, a formal model for skills and training, now superseded by SFIAPlus; International Safety Management Code, used in shipping; Kissimmee Gateway Airport (IATA airport code)
Raise a glass to 2025! Another year has come and gone, which means it’s once again time to get cozy on your couch and watch the ball drop (or watch When Harry Met Sally for the hundredth time ...
The Federal Trade Commission said there were no task scams in 2020, there were 5,000 in 2023 and then task scams quadrupled by the first half of 2024.
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