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This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
Parkinson's disease is a neurodegenerative disease described by the selective loss of dopaminergic neurons located in the substantia nigra. Today, the most commonly used drug to combat this disease is levodopa or L-DOPA. This precursor to dopamine can penetrate through the blood–brain barrier, whereas the neurotransmitter dopamine cannot ...
Pharmaceutical compound Norepinephrine Skeletal formula of noradrenaline Ball-and-stick model of the zwitterionic form of noradrenaline found in the crystal structure Clinical data Other names NE, NA, Noradrenaline, (R)-(–)-Norepinephrine, l-1-(3,4-Dihydroxyphenyl)-2-aminoethanol 3,4,β-Trihydroxyphenethylamine Physiological data Source tissues locus coeruleus ; sympathetic nervous system ...
Monoaminergic systems, i.e., the networks of neurons that use monoamine neurotransmitters, are involved in the regulation of processes such as emotion, arousal, and certain types of memory. It has also been found that monoamine neurotransmitters play an important role in the secretion and production of neurotrophin-3 by astrocytes, a chemical ...
While it may be inferred that dysfunction of 5-HT circuits is likely to be a part of the problem, it is only one of many such neurotransmitters whose signaling can be affected by suitably designed medicines attempting to alter the course of the disease state. Most common CNS disorders are highly polygenic in nature; that is, they are controlled ...
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
Statistical tests are used to test the fit between a hypothesis and the data. [1] [2] Choosing the right statistical test is not a trivial task. [1]The choice of the test depends on many properties of the research question.
Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [7] [8] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5.