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Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [151] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]
B vitamins are especially important, as deficiencies in vitamin B12, thiamin or folic acid can contribute to cognitive decline. For instance, a lack of thiamin can lead to Wernicke-Korsakoff ...
Folate (vitamin B 9) – Vitamin B 12 cobalamin: Low blood plasma and particularly red cell folate and diminished levels of vitamin B 12 have been found in patients with depressive disorders. "[W]e suggest that oral doses of both folic acid (800 μg/(mcg) daily) and vitamin B12 (1 mg daily) should be tried to improve treatment outcome in ...
Folate and vitamin B 12 play a vital role in the synthesis of S-adenosylmethionine, which is of key importance in the maintenance and repair of all cells, including neurons. [22] In addition, folate has been linked to the maintenance of adequate brain levels of cofactors necessary for chemicals reactions that lead to the synthesis of serotonin ...
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Vitamin B12 does also accumulate in a few plant-based sources, including some mushrooms, seaweed, and nutritional yeast, but not enough to fortify vegans, who, in particular, should consider being ...