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When levels are below 0.32 mmol/L (1.0 mg/dL) it is deemed to be severe. [2] Treatment depends on the underlying cause. [1] Phosphate may be given by mouth or by injection into a vein. [1] Hypophosphatemia occurs in about 2% of people within hospital and 70% of people in the intensive care unit (ICU). [1] [3]
Hypophosphatasia (/ ˌ h aɪ p oʊ ˈ f ɒ s f eɪ t ˌ eɪ ʒ ə /; also called deficiency of alkaline phosphatase, phosphoethanolaminuria, [5] or Rathbun's syndrome; [1] sometimes abbreviated HPP [6]) is a rare, and sometimes fatal, inherited [7] metabolic bone disease. [8]
Blood biochemistry should be monitored regularly until it is stable. Although clinical trials are lacking in patients other than those admitted to intensive care, it is commonly recommended that energy intake should remain lower than that normally required for the first 3–5 days of treatment of refeeding syndrome for all patients. [1]: 1.4.8
X-linked hypophosphatemia (XLH) is an X-linked dominant form of rickets (or osteomalacia) that differs from most cases of dietary deficiency rickets in that vitamin D supplementation does not cure it. It can cause bone deformity including short stature and genu varum (bow-leggedness).
Causes: Kidney failure, pseudohypoparathyroidism, hypoparathyroidism, diabetic ketoacidosis, tumor lysis syndrome, rhabdomyolysis [1] Diagnostic method: Blood phosphate > 1.46 mmol/L (4.5 mg/dL) [1] Differential diagnosis: High blood lipids, high blood protein, high blood bilirubin [1] Treatment: Decreasing intake, calcium carbonate [1 ...
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
Phosphate supplementation is used to treat hypophosphatemia.. Most hypophosphatemia occurs when phosphate leaves the circulation and enters the cells. Phosphate supplementation is often required in people who have undergone surgery and in chronically malnourished people.
In severe or acute hypoosmolar hyponatremia, swelling of brain cells causes various neurological abnormalities, which in severe or acute cases can result in convulsions, coma, and death. The symptoms of chronic syndrome of inappropriate antidiuresis are more vague, and may include cognitive impairment, gait abnormalities, or osteoporosis. [2]
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