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Mibolerone, also known as dimethylnortestosterone (DMNT) and sold under the brand names Cheque Drops and Matenon, is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was marketed by Upjohn for use as a veterinary drug.
Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. [12] [4] [6] [13] It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs.
In the United States, xylazine was approved by the FDA only for veterinary use as a sedative, analgesic, and muscle relaxant in dogs, cats, horses, elk, fallow deer, mule deer, sika deer, and white-tailed deer. [1] [3] The sedative and analgesic effects of xylazine are related to central nervous system depression. Xylazine's muscle relaxant ...
Some sources make a distinction between sterols and stanols. In this context, the difference between them is analogous to the difference between cholesterol and cholestanol, in that sterols have a double bond between C-5 and C-6, while stanols have not. [6] [a] The gonane skeleton, with the IUPAC recommended numbering of the carbon atoms
This includes inhibitory effects on lymphocyte proliferation, as in the treatment of lymphomas and leukemias, and the mitigation of side effects of anticancer drugs. Glucocorticoids affect cells by binding to the glucocorticoid receptor.
Alfaxalone is used as an induction agent, an injectable anesthetic, and a sedative in animals. [5] While it is commonly used in cats and dogs, it has also been successfully used in rabbits, [6] horses, sheep, pigs, and exotics such as red-eared turtles, axolotl, green iguanas, marmosets, [7] and koi fish. [8]
Disadvantages of mitotane as a treatment include the side effects and the requirement for blood test monitoring. Issues can arise when too much of the adrenal cortex becomes eroded. Approximately 30% of dogs will experience a reaction in response to treatment with mitotane; prednisone may be used as an antidote. In the event of a reaction ...
This steroid then makes its way throughout the cell, where it alters the permeability and rigidity of plasma membranes much as cholesterol does in animals. [3] Because ergosterol constitutes a fundamental component of fungal membranes, many antifungal medications have been developed to inhibit 14α-demethylase activity and prevent the ...