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Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder of the nervous system which prevents the feeling of pain or temperature and prevents a person from sweating. Cognitive disorders are commonly coincidental.
Type 4, congenital insensitivity to pain with anhidrosis (CIPA), is an autosomal recessive condition and affected infants present with episodes of hyperthermia unrelated to environmental temperature, anhidrosis and insensitivity to pain. Palmar skin is thickened and charcot joints are commonly present.
The diagnostic criteria for acquired idiopathic generalized anhidrosis is as follows: [6] Despite the widespread distribution of idiopathic anhidrosis or hypohidrosis lesions in a non-segmental spinal pattern, no additional neurological or autonomic symptoms are noted. [6] At least 25% of the body is affected by anhidrotic or hypohidrotic regions.
Familial dysautonomia (FD), also known as Riley–Day syndrome, is a rare, [2] progressive, [3] recessive genetic disorder of the autonomic nervous system [2] that affects the development and survival of sensory, sympathetic, and some parasympathetic neurons in the autonomic and sensory nervous system.
Individuals symptoms vary in severity and type. Severe, subacute gastrointestinal dysmotility and orthostatic hypotension are the most common symptoms in two-thirds of patients. Symptoms can be severe in some cases and gradually worsen in others. [1] Sympathetic failure manifests itself as orthostatic hypotension and anhidrosis.
Cat supplements are available that contain l-theanine and l-tryptophan. Both of these increase the monoamine neurotransmitter serotonin which acts like a hormone in the cat’s brain.