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Digitalis (/ ˌ d ɪ dʒ ɪ ˈ t eɪ l ɪ s / [3] or / ˌ d ɪ dʒ ɪ ˈ t æ l ɪ s / [4]) is a genus of about 20 species of herbaceous perennial plants, shrubs, and biennials, commonly called foxgloves. Digitalis is native to Europe, Western Asia, and northwestern Africa. The flowers are tubular in shape, produced on a tall spike, and vary in ...
Digoxin has the ability to bind oestrogen receptors, and therefore it has been proposed that it might increase the risk of oestrogen-sensitive breast and uterine cancers. [62] A large Danish study found a complicated picture, with slightly increased risk of breast cancer amongst women taking digoxin, but better prognostic features. [63]
May worsen hormone sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, and uterine fibroids. [17] Insomnia. [17] Goldenseal: orangeroot, yellow puccoon Hydrastis canadensis: Uterotonic [3] Greater celandine: celandine Chelidonium majus: Liver damage [4] Guarana: Paullinia cupana: Agitation and insomnia [3 ...
It came into use in treating cardiac disease in late 18th century England in spite of its high toxicity. a Its use has been almost entirely replaced by the pharmaceutical derivative Digoxin, which has a shorter half-life in the body, and whose toxicity is therefore more easily managed. [54] Digoxin is used as an antiarrhythmic agent and ...
Digitalis purpurea, the foxglove or common foxglove, is a toxic species of flowering plant in the plantain family Plantaginaceae, [2] native to and widespread throughout most of temperate Europe. [3] It has also naturalized in parts of North America, as well as some other temperate regions.
Digitalis lanata contains a powerful cardiac glycoside that may be used by patients with heart conditions. Digoxin (digitalin) is a drug that is extracted from D. lanata . [ 17 ] [ 18 ] It is used to treat some heart conditions such as atrial fibrillation and cardiac arrhythmias . [ 18 ]
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Unlike digoxin, which is eliminated from the body via the kidneys, it is eliminated via the liver, and so can be used in patients with poor or erratic kidney function. While several controlled trials have shown digoxin to be effective in a proportion of patients treated for heart failure, the evidence base for digitoxin is not as strong ...