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  2. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Grapefruit–drug interactions that affect the pre-systemic metabolism (i.e., the metabolism that occurs before the drug enters the blood) of drugs have a different duration of action than interactions that work by other mechanisms, such as on absorption, discussed below.

  3. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    That's why it's important to find out from your health care provider or a pharmacist if any of your medications interact with grapefruit. In addition, grapefruit can have the opposite effect on ...

  4. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

  5. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors , directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors , and their simultaneous consumption results in the overstimulation of the receptor, which can ...

  6. Can grapefruit boost your immune system and help you lose ...

    www.aol.com/news/grapefruit-boost-immune-system...

    Grapefruit, similar to other fruits, is a good source of vitamins, minerals and fiber, says Elisabetta Politi, a registered dietitian at the Duke Lifestyle and Weight Management Center in Durham ...

  7. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/grapefruit-interfere-medications...

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  8. Aliskiren - Wikipedia

    en.wikipedia.org/wiki/Aliskiren

    Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension . [ 2 ] While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.

  9. Can I Have Grapefruit with Cialis? - AOL

    www.aol.com/grapefruit-cialis-115700221.html

    Back pain. Muscle pain. Nasal congestion. ... However, care must be taken to avoid the effects of grapefruit juice when taking Cialis (namely, the increased risk of experiencing side effects).