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Because of the complex inter-relationship between analytical method, sample concentration, limits of detection and method precision, the management of Analytical Quality Control is undertaken using a statistical approach to determine whether the results obtained lie within an acceptable statistical envelope.
Quality control (QC) is a measure of precision, or how well the measurement system reproduces the same result over time and under varying operating conditions. Laboratory quality control material is usually run at the beginning of each shift, after an instrument is serviced, when reagent lots are changed, after equipment calibration, and ...
The results of testing can be qualitative (yes/no), quantitative (a measured value), or categorical and can be derived from personal observation or the output of a precision measuring instrument. Usually the test result is the dependent variable , the measured response based on the particular conditions of the test or the level of the ...
The repeatability coefficient is a precision measure which represents the value below which the absolute difference between two repeated test results may be expected to lie with a probability of 95%. [citation needed] The standard deviation under repeatability conditions is part of precision and accuracy. [citation needed]
A measurement system analysis (MSA) is a thorough assessment of a measurement process, and typically includes a specially designed experiment that seeks to identify the components of variation in that measurement process. Just as processes that produce a product may vary, the process of obtaining measurements and data may also have variation ...
A similar method was proposed in 1981 by Eksborg. [7] This method was based on Deming regression—a method introduced by Adcock in 1878.. Bland and Altman's Lancet paper [3] was number 29 in a list of the top 100 most-cited papers of all time with over 23,000 citations.
A laboratory specimen is sometimes a biological specimen of a medical patient's tissue, fluids, or other samples used for laboratory analysis to assist in differential diagnosis or staging of a disease process. These specimens are often the most reliable method of diagnosis, depending on the ailment.