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Debridement is the medical removal of dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue. [ 2 ] [ 3 ] Removal may be surgical , mechanical, chemical, autolytic (self-digestion), or by maggot therapy .
Maggot therapy (also known as larval therapy) is a type of biotherapy involving the introduction of live, disinfected maggots (fly larvae) into non-healing skin and soft-tissue wounds of a human or other animal for the purpose of cleaning out the necrotic (dead) tissue within a wound (debridement), and disinfection.
Hydrogel dressing is a medical dressing based on hydrogels, three-dimensional hydrophilic structure. [1] The insoluble hydrophilic structures absorb polar wound exudates and allow oxygen diffusion at the wound bed to accelerate healing. [ 2 ]
The vacuum may be applied continuously or intermittently, depending on the type of wound being treated and the clinical objectives. Typically, the dressing is changed two to three times per week. [3] The dressings used for the technique include foam dressings, sealed with an occlusive dressing intended to contain the vacuum at the wound site. [1]
Debridement involves the removal of dead or damaged tissue from wounds in order to assist healing. Much of the debris to be removed is proteinaceous, and proteolytic enzymes have been applied to this purpose. Papain is a protease obtained from the latex of the fruit of the papaya tree.
The release of catabolically active enzymes from their sub-cellular locations initiates an irreversible process that results in the complete reduction of deceased organisms. Autolysis produces an acidic, anaerobic, nutrient-rich environment that nurtures the activity of invasive and opportunistic microorganisms in a process known as putrefaction .