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  2. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    Scleroderma is caused by genetic and environmental factors. [ 4 ] [ 5 ] [ 17 ] [ 18 ] Mutations in HLA genes seem to play a crucial role in the pathogenesis of some cases; likewise silica , aromatic and chlorinated solvents, ketones , trichloroethylene , welding fumes, and white spirits exposure seems to contribute to the condition in a small ...

  3. List of autoimmune diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_autoimmune_diseases

    This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...

  4. Systemic scleroderma - Wikipedia

    en.wikipedia.org/wiki/Systemic_scleroderma

    Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse.

  5. List of genetic disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_genetic_disorders

    The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child. There are over 6,000 known genetic disorders in humans.

  6. Autoimmune disease - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_disease

    The exact causes of autoimmune diseases remain unclear and are likely multifactorial, involving both genetic and environmental influences. [7] While some diseases like lupus exhibit familial aggregation, suggesting a genetic predisposition , other cases have been associated with infectious triggers or exposure to environmental factors, implying ...

  7. List of skin conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_skin_conditions

    Connective tissue diseases are caused by a complex array of autoimmune responses that target or affect collagen or ground substance. [35] [43] Acute cutaneous lupus erythematosus; Atrophoderma of Pasini and Pierini (dyschromic and atrophic variation of scleroderma, morphea plana atrophica, sclérodermie atrophique d'emblée)

  8. Autoimmunity - Wikipedia

    en.wikipedia.org/wiki/Autoimmunity

    Most autoimmune diseases are sex-related; as a whole, women are much more likely to develop autoimmune disease than men. Being female is the single greatest risk factor for developing autoimmune disease than any other genetic or environmental risk factor yet discovered.

  9. Sclerosis (medicine) - Wikipedia

    en.wikipedia.org/wiki/Sclerosis_(medicine)

    Lichen sclerosus, an inflammatory skin disease that most often affects the vulva and the penis. Multiple sclerosis, or focal sclerosis, [2] is a central nervous system disease which affects coordination. Osteosclerosis, a condition where the bone density is significantly increased, resulting in decreased lucency on radiographs.

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