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Chlorpheniramine was patented in 1948 and came into medical use in 1949. [3] It is available as a generic medication and over the counter. [2] [4] In 2022, it was the 291st most commonly prescribed medication in the United States, with more than 400,000 prescriptions. [5] [6]
Voglibose was discovered in 1981, and was first launched in Japan in 1994, [2] under the trade name BASEN, to improve postprandial hyperglycemia in diabetes mellitus. [3] Postprandial hyperglycemia (PPHG) is primarily due to first phase insulin secretion. Alpha glucosidase inhibitors delay glucose absorption at the intestine level and thereby ...
Type 2 diabetes is the most common type of diabetes. Treatments include agents that (1) increase the amount of insulin secreted by the pancreas, (2) increase the sensitivity of target organs to insulin, (3) decrease the rate at which glucose is absorbed from the gastrointestinal tract, and (4) increase the loss of glucose through urination.
Pramlintide has been approved on 3/16/2005 by the FDA, for use by type 1 and type 2 diabetic patients who use insulin. [6] (subscription required) Pramlintide allows patients to use less insulin, lowers average blood sugar levels, and substantially reduces what otherwise would be a large unhealthy rise in blood sugar that occurs in diabetics right after eating.
Hydroxyzine can also be used for the treatment of allergic conditions, such as chronic urticaria, atopic or contact dermatoses, and histamine-mediated pruritus. [ medical citation needed ] These have also been confirmed in both recent and past studies to have no adverse effects on the liver, blood, nervous system, or urinary tract.
The FDA has banned Red Dye No. 3 dye from food and ingested drug products. ... Studies in other animals or in humans did not show the same effect and there is no evidence showing FD&C Red No. 3 ...