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Tegafur/uracil (abbreviation: UFT [1]) is a chemotherapy drug combination used in the treatment of cancer, primarily bowel cancer. UFT is an oral formulation combining uracil (a competitive inhibitor of dihydropyrimidine dehydrogenase ), and tegafur (a bioavailable 5-fluorouracil (5-FU) prodrug ) in a 4:1 molar ratio.
Tegafur is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers. It is a component of the combination drug tegafur/uracil . When metabolised, it becomes 5-FU.
Tegafur/gimeracil/oteracil, sold under the brand name Teysuno among others is a fixed-dose combination medication used for the treatment of advanced gastric cancer when used in combination with cisplatin, [3] and also for the treatment of head and neck cancer, colorectal cancer, non–small-cell lung, breast, pancreatic, and biliary tract cancers.
Parietal epithelial cell (PEC) Podocyte; Angioblast → Endothelial cell; Mesangial cell. Intraglomerular; Extraglomerular; Juxtaglomerular cell; Macula densa cell; Stromal cell → Interstitial cell → Telocytes; Kidney proximal tubule brush border cell; Kidney distal tubule cell; Connecting tubule cells; α-intercalated cell; β-intercalated ...
Uracil is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes. [22] Uracil is important for the detoxification of many carcinogens, for instance those found in tobacco smoke. [23] Uracil is also required to detoxify many drugs such as cannabinoids (THC) [24] and morphine (opioids). [25]
Uracil is one of the chemical building blocks for RNA, a molecule carrying directions for building and operating living organisms. Asteroid discovery suggests ingredients for life on Earth came ...
The outer red layer in this diagram is the capsule, which is distinct from the cell envelope. This bacterium is gram-positive, as its cell envelope comprises a single cell membrane (orange) and a thick peptidoglycan-containing cell wall (purple). The bacterial capsule is a large structure common to many bacteria. [1]
The blood represents both the intracellular compartment (the fluid inside the blood cells) and the extracellular compartment (the blood plasma). The average volume of plasma in the average (70-kilogram or 150-pound) male is approximately 3.5 liters (0.77 imp gal; 0.92 U.S. gal).