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1957: Marvin Minsky, a professor at MIT, invents the confocal microscope, an optical imaging technique for increasing optical resolution and contrast of a micrograph by means of using a spatial pinhole to block out-of-focus light in image formation. This technology is a predecessor to today's widely used confocal laser scanning microscope.
The optical microscope, also referred to as a light microscope, is a type of microscope that commonly uses visible light and a system of lenses to generate magnified images of small objects. Optical microscopes are the oldest design of microscope and were possibly invented in their present compound form in the 17th century.
A two-photon microscope is also a laser-scanning microscope, but instead of UV, blue or green laser light, a pulsed infrared laser is used for excitation. Only in the tiny focus of the laser is the intensity high enough to generate fluorescence by two-photon excitation , which means that no out-of-focus fluorescence is generated, and no pinhole ...
Zacharias Janssen; also Zacharias Jansen or Sacharias Jansen; 1585 – pre-1632 [1]) was a Dutch spectacle-maker who lived most of his life in Middelburg.He is associated with the invention of the first optical telescope and/or the first truly compound microscope, but these claims (made 20 years after his death) may be fabrications put forward by his son.
Léon Foucault developed a catadioptric microscope in 1859 to counteract aberrations of using a lens to image objects at high power. [2] In 1876 a French engineer, A. Mangin, invented what has come to be called the Mangin mirror, a concave glass reflector with the silver surface on the rear side of the glass. The two surfaces of the reflector ...
The light path of a bright-field microscope is extremely simple; no additional components are required beyond the normal light-microscope setup. The light path begins at the illuminator or the light source on the base of the microscope. Often a halogen lamp is used. The light travels through the objective lens into the ocular lens, through ...
The clear skies of South Florida made perfect conditions for seeing a beautiful crescent moon Friday. However, residents also got a show of a rare celestial event — a brightly lit Venus.
The stereo, stereoscopic or dissecting microscope is an optical microscope variant designed for low magnification observation of a sample, typically using light reflected from the surface of an object rather than transmitted through it. The instrument uses two separate optical paths with two objectives and eyepieces to provide slightly ...