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Buccal tablets offer many advantages over other solid dosage forms also intended for oral administration (e.g. enteric-coated tablets, chewable tablets, and capsules). Buccal tablets can be considered in patients who experience difficulty in swallowing, since these tablets are absorbed into the blood stream between the gum and cheek.
The risk of VTE with estradiol/nomegestrol acetate birth control pills is under study. [11] Incidence of irregular vaginal bleeding may be higher with estradiol-containing birth control pills in relation to the fact that estradiol is a weaker estrogen than ethinylestradiol in the endometrium. [3]
The medication is taken by mouth and contains 30 μg EE and 3 mg DRSP per tablet (brand names Yasmin, others) or 20 μg EE and 3 mg DRSP per tablet (brand names Yaz, Yasminelle, Nikki, others). [2] [3] A formulation with levomefolic acid (vitamin B 9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications.
[17] [4] However, it is thought that the antiandrogenic activity of CPA may only be significant at higher doses than are present in birth control pills. [4] [19] Both EE and CPA have antigonadotropic effects and act as contraceptives in women by suppressing ovulation. [17]
The feeling when the list of potential side effects of your birth control is approximately the same length as your high school calculus textbook. 馃槄View Entire Post ›
Estradiol-containing birth control pills were initially studied in the 1970s, with the first report published in 1977. [230] [231] Development of birth control pills containing estradiol was motivated by the thrombotic risks of ethinylestradiol that were uncovered in the 1960s and 1970s.
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These differences make EE more favorable for use in birth control pills than estradiol, though also result in an increased risk of blood clots and certain other rare adverse effects. [7] EE was developed in the 1930s and was introduced for medical use in 1943. [13] [14] The medication started being used in birth control pills in the 1960s. [15]
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