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  2. Promoter (genetics) - Wikipedia

    en.wikipedia.org/wiki/Promoter_(genetics)

    Promoters are located near the transcription start sites of genes, upstream on the DNA (towards the 5' region of the sense strand). Promoters can be about 100–1000 base pairs long, the sequence of which is highly dependent on the gene and product of transcription, type or class of RNA polymerase recruited to the site, and species of organism ...

  3. Transcriptional regulation - Wikipedia

    en.wikipedia.org/wiki/Transcriptional_regulation

    Promoter-enhancer dichotomy provides the basis for the functional interaction between transcription factors and transcriptional core machinery to trigger RNA Pol II escape from the promoter. Whereas one could think that there is a 1:1 enhancer-promoter ratio, studies of the human genome predict that an active promoter interacts with 4 to 5 ...

  4. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    Regulation of transcription in mammals. An active enhancer regulatory region of DNA is enabled to interact with the promoter DNA region of its target gene by the formation of a chromosome loop. This can initiate messenger RNA (mRNA) synthesis by RNA polymerase II (RNAP II) bound to the promoter at the transcription start site of the gene. The ...

  5. Enhancer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Enhancer_(genetics)

    Regulation of transcription in mammals. An active enhancer regulatory region of DNA is enabled to interact with the promoter DNA region of its target gene by the formation of a chromosome loop. This can initiate messenger RNA (mRNA) synthesis by RNA polymerase II (RNAP II) bound to the promoter at the transcription start site of the gene. The ...

  6. TATA box - Wikipedia

    en.wikipedia.org/wiki/TATA_box

    Additional transcription factors then bind, first TFIIE and then TFIIH. [24] This completes the assembly of the preinitiation complex for eukaryotic transcription. [3] Generally, the TATA box is found at RNA polymerase II promoter regions, although some in vitro studies have demonstrated that RNA polymerase III can recognize TATA sequences. [25]

  7. Regulatory sequence - Wikipedia

    en.wikipedia.org/wiki/Regulatory_sequence

    Regulation of transcription in mammals. An active enhancer regulatory sequence of DNA is enabled to interact with the promoter DNA regulatory sequence of its target gene by formation of a chromosome loop. This can initiate messenger RNA (mRNA) synthesis by RNA polymerase II (RNAP II) bound to the promoter at the transcription start site of the ...