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MSA was first described in 1960 by Milton Shy and Glen Drager and was then known as Shy–Drager syndrome. [2] Many people affected by MSA experience dysfunction of the autonomic nervous system, which commonly manifests as orthostatic hypotension, impotence, loss of sweating, dry mouth and urinary retention and incontinence.
Additional Parkinson-plus syndromes include Pick's disease and olivopontocerebellar atrophy. [7] The latter is characterized by ataxia and dysarthria, and may occur either as an inherited disorder or as a variant of multiple system atrophy. MSA is also characterized by autonomic failure, formerly known as Shy–Drager syndrome. [8]
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
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In 1997, during a trip to New York City, Cash was diagnosed with the neurodegenerative disease Shy–Drager syndrome, a form of multiple system atrophy. [112] According to biographer Robert Hilburn, the disease was originally misdiagnosed as Parkinson's disease , and Cash even announced to his audience that he had Parkinson's after nearly ...
Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. [3]
Shy–Drager syndrome is a rare neurodegenerative disease that attacks the autonomic nervous system. Since the main symptom of Shy–Drager syndrome is incontinence it makes it a good candidate to study its effects on Onuf's nucleus. When the sacral sections of the spinal cord were studied in patients with Shy–Drager syndrome, it was revealed ...
Multiple system atrophy; N. ... New Brunswick neurological syndrome of unknown cause; ... Shy-Drager syndrome; Spinocerebellar ataxia;