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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
Spastic hypertonia involves uncontrollable muscle spasms, stiffening or straightening out of muscles, shock-like contractions of all or part of a group of muscles, and abnormal muscle tone. It is seen in disorders such as cerebral palsy, stroke, and spinal cord injury. Rigidity is a severe state of hypertonia where muscle resistance occurs ...
Noma—a gangrenous disease still widespread among malnourished children living on the borders of the Sahara desert—can cause ankylosis of the maxilla and mandible, impairing the ability to speak and eat. [4] Fibrodysplasia ossificans progressiva is a rare bone disease in which muscle, tendons and ligaments turn to bone. This leads to ...
A neuromuscular disease is any disease affecting the peripheral nervous system (PNS), [a] the neuromuscular junctions, or skeletal muscles, all of which are components of the motor unit. [4] Damage to any of these structures can cause muscle atrophy and weakness. Issues with sensation can also occur. Neuromuscular diseases can be acquired or ...
Rigidity is characterized by an increased muscle tone (an excessive and continuous contraction of the muscles) which produces stiffness and resistance to movement in joints. [1] Rigidity may be associated with joint pain, with such pain being a frequent initial manifestation of the disease. [1]
Myotonia congenita is a congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder.The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles and rigidity. [1]
For example, their joints may be easily injured, be more prone to complete or partial dislocation due to the weakly stabilized joint and they may develop problems from muscle fatigue (as muscles must work harder to compensate for weakness in the ligaments that support the joints). Hypermobility syndromes can lead to chronic pain or even ...
Cadaveric spasm can be distinguished from rigor mortis as the former is a stronger stiffening of the muscles that cannot be easily undone, while rigor mortis can. [2] The cause is unknown but is usually associated with violent deaths under extreme physical circumstances with intense emotion, such as the circumstances associated with death via ...