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Diabetic cheiroarthropathy, also known as diabetic stiff hand syndrome or limited joint mobility syndrome, is a cutaneous condition characterized by waxy, thickened skin and limited joint mobility of the hands and fingers, leading to flexion contractures, a condition associated with diabetes mellitus [1]: 681 and it is observed in roughly 30% of diabetic patients with longstanding disease.
Diabetes mellitus type 1 [2] Pancreatic beta cell proteins (possibly insulin, glutamate decarboxylase) Insulitis, beta cell destruction Granulomas [3] Various, depending on underlying disease Walled-off lesion containing macrophages and other cells Some peripheral neuropathies: Schwann cell antigen Neuritis, paralysis: Hashimoto's thyroiditis [2]
[1] Type 2 diabetes is a progressive condition in which the body becomes resistant to the normal effects of insulin and/or gradually loses the capacity to produce enough insulin in the pancreas. [2] Pre-diabetes means that the blood sugar level is higher than normal but not yet high enough to be type 2 diabetes. [3]
A drug treatment for type 2 diabetes; belongs to a class of drugs called biguanides. First-line pharmacotherapy for type 2 diabetes mellitus. Mg/dL Milligrams per deciliter. How much glucose (sugar) is in a specific amount of blood. In self-monitoring of blood glucose, test results are given as the amount of glucose in milligrams per deciliter ...
The cone on the Hawaiian earring is contractible and therefore simply connected, but still not locally simply connected. All topological manifolds and CW complexes are locally simply connected. In fact, these satisfy the much stronger property of being locally contractible. A strictly weaker condition is that of being semi-locally simply ...
Diabetic angiopathy is a form of angiopathy associated with diabetic complications. [1] While not exclusive, the two most common forms are diabetic retinopathy and diabetic nephropathy, whose pathophysiologies are largely identical. Other forms of diabetic angiopathy include diabetic neuropathy and diabetic cardiomyopathy. [2] [3]
The glucose clamp technique was developed by University of Texas (UT) School of Medicine Professors DeFronzo, Andres and Tobin in 1979. [2] It has since been the gold standard for pharmacodynamic studies in diabetes drug development and diagnostics evaluation. [3]
The dunce hat is contractible, but not collapsible. Contractibility can be easily seen by noting that the dunce hat embeds in the 3-ball and the 3-ball deformation retracts onto the dunce hat. Alternatively, note that the dunce hat is the CW-complex obtained by gluing the boundary of a 2-cell onto the circle.
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