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Piperidine is used as a solvent and as a base. The same is true for certain derivatives: N-formylpiperidine is a polar aprotic solvent with better hydrocarbon solubility than other amide solvents, and 2,2,6,6-tetramethylpiperidine is a highly sterically hindered base, useful because of its low nucleophilicity and high solubility in organic ...
N-Formylpiperidine is an organic compound with the formula C 6 H 11 NO. It is the amide of formic acid and piperidine.It can be used as a polar aprotic solvent, with better hydrocarbon solubility than other amide solvents such as dimethylformamide (DMF). [1]
solvent N-benzyl-4-piperidone fentanyl: chloroephedrine methamphetamine Butyrophenone: substituted cathinones: Valerophenone: substituted cathinones: Propiophenone: substituted cathinones: 2C-H: 2C-x and DOx: 2-bromo-1-(4-chlorophenyl)propan-1-one substituted cathinones and substituted amphetamines: 2-bromo-1-(4-methoxyphenyl)propan-1-one
Pyridine is used as a polar, basic, low-reactive solvent, for example in Knoevenagel condensations. [24] [113] It is especially suitable for the dehalogenation, where it acts as the base for the elimination reaction. In esterifications and acylations, pyridine activates the carboxylic acid chlorides and anhydrides.
This page contains tables of azeotrope data for various binary and ternary mixtures of solvents. The data include the composition of a mixture by weight (in binary azeotropes, when only one fraction is given, it is the fraction of the second component), the boiling point (b.p.) of a component, the boiling point of a mixture, and the specific gravity of the mixture.
4-Piperidone is an organic compound with the molecular formula OC(CH 2) 4 NH.It can be viewed as a derivative of piperidine. 4-Piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs.
20% piperidine in DMF (Fmoc group has an approximate half life of 6 seconds in this solution) [8] 5% piperazine, 1% DBU and 1% formic acid in DMF. This method avoids the use of strictly controlled piperidine. [9] No side product was observed for a peptide with 9 residues synthesized with this method. [10]
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