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Excel maintains 15 figures in its numbers, but they are not always accurate; mathematically, the bottom line should be the same as the top line, in 'fp-math' the step '1 + 1/9000' leads to a rounding up as the first bit of the 14 bit tail '10111000110010' of the mantissa falling off the table when adding 1 is a '1', this up-rounding is not undone when subtracting the 1 again, since there is no ...
Data reconciliation is a technique that targets at correcting measurement errors that are due to measurement noise, i.e. random errors.From a statistical point of view the main assumption is that no systematic errors exist in the set of measurements, since they may bias the reconciliation results and reduce the robustness of the reconciliation.
For example, the 68% confidence limits for a one-dimensional variable belonging to a normal distribution are approximately ± one standard deviation σ from the central value x, which means that the region x ± σ will cover the true value in roughly 68% of cases. If the uncertainties are correlated then covariance must be taken into account ...
Data cleansing may also involve harmonization (or normalization) of data, which is the process of bringing together data of "varying file formats, naming conventions, and columns", [2] and transforming it into one cohesive data set; a simple example is the expansion of abbreviations ("st, rd, etc." to "street, road, etcetera").
As with the ¯ and s and individuals control charts, the ¯ chart is only valid if the within-sample variability is constant. [4] Thus, the R chart is examined before the x ¯ {\displaystyle {\bar {x}}} chart; if the R chart indicates the sample variability is in statistical control, then the x ¯ {\displaystyle {\bar {x}}} chart is examined to ...
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By minimizing these systematic variations, true biological differences can be found. To determine whether normalization is needed, one can plot Cy5 (R) intensities against Cy3 (G) intensities and see whether the slope of the line is around 1. An improved method, which is basically a scaled, 45 degree rotation of the R vs. G plot is an MA-plot. [4]