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Individual dogs of any breed can have a profound reaction characterized by hypotension, especially if there is an underlying heart problem. In giant-breed dogs and sighthounds, the sedative effects of acepromazine may last for 12–24 hours, which is much longer than the usual 3–4 hours. [16] [20]
Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. [3] Common side effects may include vomiting, headache, blurred vision, and muscle weakness. [3] Severe side effects may include allergic reactions, retinopathy, and irregular heart rate.
Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]
pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID) phenylpropanolamine – controls urinary incontinence in dogs
Side-effects, drug interactions, and allergenic sensitivities are concerns when administering any medication to a person's dog. The Canine Liver Disease Foundation claims that many common drugs also can lead to liver damage in dogs, although they do not specifically cite any of the abovementioned drugs prescribed for dog anxiety.
However, researchers recently carried out a study looking at the effects of an age-reversal pill on dogs, and – while it might sound like something from a sci-fi movie – their findings give us ...