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Scientists have identified a biomarker for Alzheimer's that may help doctors spot the early signs of protein buildup in the brain before it causes significant damage. New test may detect Alzheimer ...
The study was focused on analyzing tau, a protein in the brain that plays a key role in Alzheimer's. In people with the neurological disease, tau proteins undergo chemical changes, forming tangled ...
The biochemistry of Alzheimer's disease, the most common cause of dementia, is not yet very well understood. Alzheimer's disease (AD) has been identified as a proteopathy: a protein misfolding disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. [1]
Subtle changes in brain activity in the presence of both amyloid-beta and tau proteins may point to Alzheimer's disease, long before symptoms appear, a new study indicates.
Neurofibrillary tangles (NFTs) are intracellular aggregates of hyperphosphorylated tau protein that are most commonly known as a primary biomarker of Alzheimer's disease. Their presence is also found in numerous other diseases known as tauopathies .
The causes of Alzheimer's disease remain poorly understood. [16] There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. [17] [18] Other risk factors include a history of head injury, clinical depression, and high blood pressure. [1]
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